Protein name:
Frizzled-3 (Fz-3;cFz-3) ;
Alternative:
Organism:
Chicken (Gallus gallus).
General Annotation
Function:
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Subcellular Location:
Membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
YPERPIIFYA | VCYMMVSLIF | FIGFLLEDRV | ACNASSPAQY | KASTVTQGSH |
76:
NKACTMLFMV | LYFFTMAGSV | WWVILR
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Chicken
Mouse
ELISA Kit for Chicken Fz-3
ELISA Kit for Chicken Fz-3
ELISA Kit for Chicken Fz-3
CLIA Kit for Chicken Fz-3
CLIA Kit for Chicken Fz-3
CLIA Kit for Chicken Fz-3
Polyclonal Antibody for Chicken Fz-3
Polyclonal Antibody for Chicken Fz-3
Polyclonal Antibody for Chicken Fz-3
Monoclonal Antibody for Chicken Fz-3
Monoclonal Antibody for Chicken Fz-3
Monoclonal Antibody for Chicken Fz-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Limb bud .